The long-term effects of infection on the immune system have long intrigued John Tsang, a Yale immunobiologist. After the body has faced down a pathogen, does the immune system return to the previous baseline? Or does a single infection change it in ways...
As the COVID-19 pandemic showed, potentially dangerous new viruses can begin to spread in the population well before the global public health surveillance system can detect them.
However, Yale researchers have found that testing for the presence of a...
The investigational drug lecanemab slowed clinical decline in participants with early-stage Alzheimer’s disease by 27% after 18 months of treatment compared with participants who received a placebo, a phase 3 clinical trial has reported.
The results of...
Neuroimaging technology has been shown to hold great promise in helping clinicians link specific symptoms of mental health disorders to abnormal patterns of brain activity. But a new Yale-led study shows there are still kinks to be ironed out before...
Two Yale labs will lead projects, in collaboration with other leading research universities, tasked with developing new approaches to understand and combat pathogens. The ambitious projects will be funded by the Howard Hughes Medical Institute’s (HHMI)...
Omicron subvariants of SARS-CoV-2 — the virus behind COVID-19 — have shown an uncanny knack for evading antibodies produced either by vaccines or exposure to earlier versions of the virus, leading to many breakthrough infections. However, in order to...
The U.S. prison population plummeted during the early months of the COVID-19 pandemic but the percentage of incarcerated Black people rose, according to a new analysis of prison data published April 19 in the journal Nature.
The higher percentage of...
What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, according to a new study led by researchers at Yale and the...
Every day stem cells in the human body help replace billions of cells lost in the regular, homeostatic maintenance of our organs. But while scientists have investigated the cellular regulators of this balanced cycle of production-and-loss for years, it...
When it was launched in April 2003, the Human Genome Project helped revolutionize biomedical research by providing scientists a reference map that allowed them to analyze DNA sequences for genetic clues to the origins of a host of diseases.
Twenty years...