Yale University researchers have developed a novel vaccine that in guinea pigs offers protection against infection by the bacterium that causes Lyme disease and may also combat other tick-borne diseases, they report Nov. 17 in the journal Science...
From 50,000 years to 6,000 years ago, many of the world’s largest animals, including such iconic grassland grazers as the woolly mammoth, giant bison, and ancient horses, went extinct. The loss of these grazing species triggered a dramatic increase in...
Mutations of a gene that regulates formation of blood vessels in the brain of vertebrates can lead to potentially deadly aneurysms in adults, Yale School of Medicine researchers report in the December issue of Nature Medicine.
Saccular brain aneurysms...
Scientists in recent years have developed ways to measure biological age by tracking chemical changes in DNA that occur naturally as people age but occur at different times in different people. These so-called “epigenetic clocks” have proved to be better...
In the past decade, immunotherapy has helped save the lives of many cancer patients, many with lung cancer, who might have otherwise faced almost certain death sentences. However, only about 20% of patients who received immune therapies, designed to...
Why do 80 to 90% of people infected with COVID-19 experience only mild cases while 10 to 20% face more severe or life-threatening symptoms?
Researchers in the lab of Yale’s Richard Flavell decided to pose this question to a mouse, or rather to mice they...
The emergence of COVID-19 variants such as Delta and Omicron have sent scientists scrambling to determine whether existing vaccinations and boosters are still effective against new strains of SARS-Cov-2.
A new response to the rapidly mutating virus might...