When new COVID-19 vaccines were first administered two years ago, public health officials found an increase in cases of myocarditis, an inflammation of the heart muscle, particularly among young males who had been vaccinated with mRNA vaccines. It was...
A study of more than 22,000 people with multiple sclerosis (MS) has for the first time identified a genetic variant associated with faster progression of the disease, an accumulation of disability that can rob patients of their mobility and independence...
Vaccines that spur the creation of antibodies designed to attack specific spike proteins of the SARS-CoV-2 virus have been the principal defense against COVID-19. However, Yale researchers have found that local cells that line airways of the respiratory...
The role played by mutations in the LRRK2 gene in promoting Parkinson’s disease has long intrigued scientists, and even led to an experimental drug that inhibits the over-active protein. Yet exactly how LRRK2 triggers this devastating neurodegenerative...
All humans have a diverse set of blood stem cell types which dictate the composition and function of our blood and immune cells and ultimately help govern overall health. Older people tend to lose this diversity of blood stem cells, which can make them...
In a promising form of immunotherapy known as CAR T-cell (chimeric antigen receptor) therapy, the patient’s T cells are engineered to better recognize and attack antigens on the surface of cancer cells. In treatments currently approved for use in battling...
Two distinct neurodevelopmental abnormalities that arise just weeks after the start of brain development have been associated with the emergence of autism spectrum disorder, according to a new Yale-led study in which researchers developed brain organoids...
Yale researchers have created a functional “humanized” liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting tens of millions of...
Music can take on many forms in cultures across the globe, but Yale researchers have found in a new study that some themes are universally recognizable by people everywhere with one notable exception — love songs.
“All around the world, people sing in...
People who have experienced brain fog, confusion, pain, and extreme fatigue for months or longer after being infected with the COVID-19 virus exhibit different immune and hormonal responses to the virus than those not diagnosed with long COVID, according...