Many patients treated for metastatic melanoma develop resistance to an otherwise effective drug therapy known as BRAF inhibitors, which targets a specific genetic mutation. The cause of this resistance in 40% of patients is unclear. Yale researchers...
More than 70% of researchers failed to reproduce another scientist’s experiment, according to a survey conducted by Nature in 2016. If scientists can’t reproduce each other’s work, important discoveries may never leave the lab and have an impact on human...
By targeting a protein found in the saliva of mosquitoes that transmit Zika virus, Yale investigators reduced Zika infection in mice. The finding demonstrates how researchers might develop a vaccine against Zika and similar mosquito-borne viruses, the...
Scientists have recently recognized that cells of the same type can behave differently in response to stimulation. In a new study, Yale researchers have shown how these varied responses are due in part to a desynchronized molecular “clock” within cell...
As the opioid overdose epidemic continues to take its toll, causing 47,600 deaths in 2017, researchers continue to seek innovative solutions to the crisis. At Yale, a team of medical experts and students have come up with a tool that could help individual...
Yale School of Medicine faculty have been awarded $40 million in grants to study medication treatment for veterans with opioid addiction.
Drs. Ismene Petrakis and Sandra Springer are co-principal investigators leading the research, which is supported by...
State breast density notification laws that mandate reporting of mammogram results can prompt further screening and modestly boost cancer detection rates, say researchers at Yale’s School of Public Health and School of Medicine. Their study was published...
Compared to privately insured patients, individuals who lack insurance or use Medicaid are more likely to be transferred to another hospital after receiving initial treatment in the emergency department (ED). The uninsured are also at greater risk of...
In a new study of patients awaiting kidney transplants, Yale researchers found significant racial disparities. This occurred despite a new system designed to reduce inequities, the researchers said.
The study was published in JAMA Surgery.
in 2014, the...
In up to 30% of individuals with chronic liver disease, the cause is unknown. To test for possible genetic factors in such cases, Yale researchers conducted whole-exome sequencing for a small group of patients, finding specific mutations that would have...
