Brain organoids created from human embryonic stem cells offer scientists a powerful way to study the developing brain in three dimensions. However, organoids need nutrients and oxygen carried in blood to thrive, just as a developing fetal brain does. Now...
A group of Yale scientists have devised a way to leverage artificial neural networks to reveal larger patterns of activity of individual cells that come from a multitude of individuals.
In a paper published Oct. 7 in the journal Nature Methods,...
Doctors routinely recommend surgery for patients who suffer brain hemorrhages near the brain stem in an area called the cerebellum. However, an international meta-analysis shows that while patients who undergo surgery for intracerebral hemorrhage (ICH)...
Age-related macular degeneration is one of the leading causes of blindness in the elderly, affecting more than 2 million people in the United States and leading to progressive loss of central vision. Genome wide studies have identified almost three dozen...
The progression of cancer has been studied extensively, and the key steps in this journey have been well mapped, at least in some solid tumors: Lesions to genes that confer risk of cancer accumulate and alter normal cell behaviors, giving rise, scientists...
Yale’s Nenad Sestan M.D., Ph.D., the Harvey and Kate Cushing Professor of Neuroscience, has been named as one of Nature’s 10 scientists who made a difference in 2019, the journal announced Dec. 17.
The journal recognized the work of Sestan and his team...
In the last decade, scientists discovered that blocking a key regulator of the immune system helped unleash the body’s natural defenses against several forms of cancer, opening up a new era of cancer immunotherapy. Now Yale scientists have essentially...
For as many as one in three people, life events or situations that pose no real danger can spark a disabling fear, a hallmark of anxiety and stress-related disorders. Cognitive behavioral therapy and antidepressants help about half the people suffering...
Scientists now have the ability to collect massive amounts of data on life’s most fundamental processes, such as the intricate choreography whereby a handful of embryonic stem cells give rise to trillions of specialized cells throughout the human body....
David Post, professor of ecology and evolutionary biology at Yale, has been named a fellow of the American Association for the Advancement of Science (AAAS).
Post was elected to the AAAS by his peers for his “distinguished contributions to our...