Yale researchers have developed a way to target RNA with small-molecule drugs, creating a new method for tapping into a vast number of biological mechanisms critical to metabolism and gene expression.
“There is tremendous interest in targeting RNA with...
Yale doctors have developed a way to create vascular grafts from stem cells that are as strong as the original blood vessels they would replace.
The advance, demonstrated in an animal model, may lead to bioengineered grafts suitable for transplant into...
Before scientists develop the bioengineered tissue of tomorrow for treating pulmonary diseases, they need to identify the best methods for growing tissue for artificial trachea and lungs in experiments today.
A new Yale analysis does just that,...
Amid the whirlwind of changes to campus life wrought by the onset and spread of coronavirus-2019 (COVID-19), the Yale Center for Genome Analysis is performing a vital role in the fight against the virus.
The center, located on Yale’s West Campus, is one...
One of the biggest challenges facing scientists, public health experts, and society itself during the COVID-19 crisis is the need to develop an effective vaccine for the virus that causes the disease.
Researchers around the world are racing to develop...
A week after Yale closed its labs to all but the most critical work amid the COVID-19 pandemic, Eric Paulson, director of the Chemical and Biophysical Instrumentation Center (CBIC), got a request.
New England Discovery Partners, a small, contract research...
Behind every good idea for a drug to fight COVID-19, there’s often a good library of chemicals.
At Yale, that library is at the Yale Center for Molecular Discovery (YCMD) — home to collections of 300,000 small molecules and 18,000 genomic probes....
Yale University scientists have developed a novel chemical process that may lead to the creation of a new class of antibiotics.The discovery comes at a time when more types of bacteria are becoming resistant to existing antibiotics, increasing the...
Sarecycline, a drug approved for use in the United States in 2018, is the first new antibiotic approved to treat acne in more than 40 years. Now, researchers at Yale and the University of Illinois-Chicago have discovered how its unique chemical structure...