Immunotherapy has revolutionized the treatment of cancer in the last decade, yet many tumors do not respond to these new therapies. A new genome-wide screen of 20,000 human genes in T cells have turned up several new candidates to unleash the immune...
As cells age, they accumulate signs of DNA damage. Breaks in both strands of the DNA molecule are especially toxic and have been linked to increased genomic instability and cancer risk with age. A new Yale study of yeast quantifies how the age of a cell...
Attitudes towards lesbians and gay men can be shaped early on in medical training, with early-career doctors expressing less bias towards sexual minorities two years after medical school the more contact and favorable interactions they had with members of...
The Yale School of Medicine been designated as one of four Parkinson’s Foundation Research Centers, the foundation announced July 30. The Parkinson’s Foundation awarded each center $2 million over five years “to drive innovative research developments and...
Post-stroke management — particularly the regulation of blood pressure — is crucial to achieve the best outcome for patients. However, normal regulation of blood flow to the brain can be disrupted by stroke. If a patient’s blood pressure is too low, brain...
Symptoms of post-traumatic stress disorder (PTSD) overlap with several other psychiatric disorders, but one specific symptom — repeated disturbing memories and flashbacks about a specific event — is a defining characteristic of debilitating PTSD.
A new...
Even in patients who receive long-term anti-retroviral treatment, cells containing HIV remain in the cerebrospinal fluid of half of those treated for the disease, and those individuals are more likely to experience cognitive deficits than those without...
A prevailing theory in neuroscience holds that people make decisions based on integrated global calculations that occur within the frontal cortex of the brain.
However, Yale researchers have found that three distinct circuits connecting to different...
Of all forms of memory, episodic memory is the most intimate. We recall the sequences of events that happen to us — a marriage, a visit to a foreign country, a personal achievement — in great autobiographical detail. But scientists have disagreed about...