Much of the research on HIV has focused on preventing infection but little is understood about how the body keeps the virus in check post-infection. A new study by Yale investigators reveals the role of a protein that serves to block HIV gene expression...
More and more hospitalized patients with sepsis are being diagnosed with a deadly complication characterized by high levels of inflammation. A team of Yale researchers has uncovered clues to the cause of this complication — which kills up to 80% of...
More than 70% of researchers failed to reproduce another scientist’s experiment, according to a survey conducted by Nature in 2016. If scientists can’t reproduce each other’s work, important discoveries may never leave the lab and have an impact on human...
Scientists have recently recognized that cells of the same type can behave differently in response to stimulation. In a new study, Yale researchers have shown how these varied responses are due in part to a desynchronized molecular “clock” within cell...
By targeting a protein found in the saliva of mosquitoes that transmit Zika virus, Yale investigators reduced Zika infection in mice. The finding demonstrates how researchers might develop a vaccine against Zika and similar mosquito-borne viruses, the...
The best hope for people with an inherited form of kidney disease that causes kidney failure is dialysis or a kidney transplant. But a study led by Yale researchers reveals a potential strategy for developing new drug therapies for these patients.
Senior...
What drives the social bond between offspring and caregivers in the first few days of life? A Yale-led team of researchers has found clues in specific neurons in the brains of neonatal mice that are associated with feeding.
The neurons, known as Agrp,...
Each month during women’s reproductive years, the uterus sheds and regenerates the tissue lining its walls in preparation for a pregnancy or the next cycle. The process behind this age-old and essential part of human reproduction is not well understood....
What makes healthy cells change and become dysfunctional to the point of causing disease? In addition to a disruption in genes that regulate cells, there is another factor in cell misbehavior that involves metabolism, say Yale researchers.
The research...