Brain organoids created from human embryonic stem cells offer scientists a powerful way to study the developing brain in three dimensions. However, organoids need nutrients and oxygen carried in blood to thrive, just as a developing fetal brain does. Now...
A group of Yale scientists have devised a way to leverage artificial neural networks to reveal larger patterns of activity of individual cells that come from a multitude of individuals.
In a paper published Oct. 7 in the journal Nature Methods,...
Cancer cells are masters at avoiding detection, but a new system developed by Yale scientists can make them stand out from the crowd and help the immune system spot and eliminate tumors that other forms of immunotherapies might miss, the researchers...
Many neurodevelopmental disorders such as epilepsy, schizophrenia, and autism have been linked to disruption of the key neurotransmitter GABA, but the underlying causes of the disruptions have been difficult to pinpoint. In two new papers published Oct....
The lab of Stephen Waxman, Bridget M. Flaherty Professor of Neurology and of neuroscience, has identified the key role of sodium channels arrayed on nerve cells in experience of pain.
In a new paper published in Science Advances, the Yale team led by...
Age-related macular degeneration is one of the leading causes of blindness in the elderly, affecting more than 2 million people in the United States and leading to progressive loss of central vision. Genome wide studies have identified almost three dozen...
Scientists have looked for immune system factors that might help mosquitoes ward off pathogens such as malarial parasites and indirectly protect humans from infection. Yale researchers found one by editing a single gene, which turns out to be crucial for...