The progression of cancer has been studied extensively, and the key steps in this journey have been well mapped, at least in some solid tumors: Lesions to genes that confer risk of cancer accumulate and alter normal cell behaviors, giving rise, scientists...
In the last decade, scientists discovered that blocking a key regulator of the immune system helped unleash the body’s natural defenses against several forms of cancer, opening up a new era of cancer immunotherapy. Now Yale scientists have essentially...
For as many as one in three people, life events or situations that pose no real danger can spark a disabling fear, a hallmark of anxiety and stress-related disorders. Cognitive behavioral therapy and antidepressants help about half the people suffering...
A high-fat, low-carbohydrate diet like the Keto regimen has its fans, but influenza apparently isn’t one of them.
Mice fed a ketogenic diet were better able to combat the flu virus than mice fed food high in carbohydrates, according to a new Yale...
Scientists have looked for immune system factors that might help mosquitoes ward off pathogens such as malarial parasites and indirectly protect humans from infection. Yale researchers found one by editing a single gene, which turns out to be crucial for...
Age-related macular degeneration is one of the leading causes of blindness in the elderly, affecting more than 2 million people in the United States and leading to progressive loss of central vision. Genome wide studies have identified almost three dozen...
The lab of Stephen Waxman, Bridget M. Flaherty Professor of Neurology and of neuroscience, has identified the key role of sodium channels arrayed on nerve cells in experience of pain.
In a new paper published in Science Advances, the Yale team led by...
Six Yale faculty members have been elected to the National Academy of Medicine (NAM), the organization announced Oct. 21 at its annual meeting.
The six faculty are among 100 new members elected by the organization to receive the honor, which recognizes...
The National Institutes of Health (NIH) through the Rare Diseases Clinical Research Consortia (RDCRC) has awarded a research team from Yale University, George Washington University, and Duke University $7.8 million to establish a rare disease network for...
Many neurodevelopmental disorders such as epilepsy, schizophrenia, and autism have been linked to disruption of the key neurotransmitter GABA, but the underlying causes of the disruptions have been difficult to pinpoint. In two new papers published Oct....