A group of Yale scientists have devised a way to leverage artificial neural networks to reveal larger patterns of activity of individual cells that come from a multitude of individuals.
In a paper published Oct. 7 in the journal Nature Methods,...
Brain organoids created from human embryonic stem cells offer scientists a powerful way to study the developing brain in three dimensions. However, organoids need nutrients and oxygen carried in blood to thrive, just as a developing fetal brain does. Now...
Aristotle was puzzled. Freud had his own ideas. But no one theory has satisfactorily answered the question: Why do women have orgasms?
Orgasms in human females are not necessary for reproduction. The clitoris, which stimulates orgasm, is situated north of...
The way we see the world around us is the result of a marriage of two neural pathways — one shared by all vertebrates and one that evolved in mammals more recently. It has been a mystery to scientists how these two networks emerge in development to help...
The Yale laboratory of Sidi Chen, assistant professor of genetics in the Systems Biology Institute and Yale Cancer Center, has developed advanced gene-editing and screening technology to find new targets for cancer immunotherapy.
In a new study published...
Yale scientists have found missing molecular “fossils” that shed light on a key event in the early evolution of life on earth — the origin of the cell nucleus — they report online Sept. 10 in the journal Molecular Biology and Evolution.
The nucleus...
Scientists have long searched for “driver” genes that fuel the progression of cancer, but existing technology has had a hard time separating mutations that are true drivers from others that are simply “passengers,” not directly involved in spread of...
Immunotherapy has revolutionized the treatment of cancer in the last decade, yet many tumors do not respond to these new therapies. A new genome-wide screen of 20,000 human genes in T cells have turned up several new candidates to unleash the immune...