More than 70% of researchers failed to reproduce another scientist’s experiment, according to a survey conducted by Nature in 2016. If scientists can’t reproduce each other’s work, important discoveries may never leave the lab and have an impact on human...
More and more hospitalized patients with sepsis are being diagnosed with a deadly complication characterized by high levels of inflammation. A team of Yale researchers has uncovered clues to the cause of this complication — which kills up to 80% of...
Much of the research on HIV has focused on preventing infection but little is understood about how the body keeps the virus in check post-infection. A new study by Yale investigators reveals the role of a protein that serves to block HIV gene expression...
When scientists probe the human genome for clues about disease, they typically focus on the 2% of our genome that make functional proteins. To explore underexamined elements in the genome, a team of Yale investigators developed a tool, called ERVmap, that...
More than one million people die annually from cerebral malaria, the most lethal form of the disease. A recent study, led by Yale investigators, explores the role of glucose metabolism in the development of the disease, and may hold a key to preventing or...
For human cells to form and move normally during development, a network of protein filaments, known as the actin cytoskeleton, must organize the cell’s shape from within. To help rearrange this network, another protein known as filamin must bind and...
Yale researchers have developed a new imaging technique that captures detailed information about metabolism, which plays a role in many diseases. The novel yet simple technique, which harnesses existing technology, could potentially be used to evaluate...