Fat cells are filled with droplets coated by molecules that act like hotel doormen: These “doormen” control cellular access for nutrients as well as for the exit of energy-supplying molecules called lipids. In healthy individuals, outgoing and incoming...
The peaceful and delicate co-existence of friendly gut bacteria and the immune system relies on highly coordinated information exchange between immune system cells and certain cells lining the intestine. Until now, scientists generally believed these two...
Yale’s Nenad Sestan M.D., Ph.D., the Harvey and Kate Cushing Professor of Neuroscience, has been named as one of Nature’s 10 scientists who made a difference in 2019, the journal announced Dec. 17.
The journal recognized the work of Sestan and his team...
Scientists now have the ability to collect massive amounts of data on life’s most fundamental processes, such as the intricate choreography whereby a handful of embryonic stem cells give rise to trillions of specialized cells throughout the human body....
A high-fat, low-carbohydrate diet like the Keto regimen has its fans, but influenza apparently isn’t one of them.
Mice fed a ketogenic diet were better able to combat the flu virus than mice fed food high in carbohydrates, according to a new Yale...
Yale’s Arthur L. Horwich and his colleague and collaborator F. Ulrich Hartl from the Max Planck Institute were among distinguished scientists feted at the Breakthrough Prize gala awards ceremony Nov. 3 at the NASA Ames Research Center in Mountain View,...
Scientists routinely capture images of the brain in action by focusing on single molecules, cells, or circuits. But visualizing how these tiny units interact to create complex behavior has been a daunting task. Now, in a collaborative, multi-lab effort,...
Scientists have looked for immune system factors that might help mosquitoes ward off pathogens such as malarial parasites and indirectly protect humans from infection. Yale researchers found one by editing a single gene, which turns out to be crucial for...
Age-related macular degeneration is one of the leading causes of blindness in the elderly, affecting more than 2 million people in the United States and leading to progressive loss of central vision. Genome wide studies have identified almost three dozen...
The lab of Stephen Waxman, Bridget M. Flaherty Professor of Neurology and of neuroscience, has identified the key role of sodium channels arrayed on nerve cells in experience of pain.
In a new paper published in Science Advances, the Yale team led by...