More than 60% of all drugs, including antibiotics and cancer treatments, are derived from natural products in the form of small molecules encoded by metabolic genes. These molecules often form complex chemical structures, shaped by billions of years of...
As Yale seeks to expand the diversity and excellence of its faculty, the Department of Molecular Biophysics and Biochemistry (MB&B) has developed a novel way of identifying promising candidates.
Last year, MB&B Chair Enrique M. De La Cruz and...
One proposed strategy in the fight against climate change is to increase tree cover in the world’s savannas, either through the planting of new trees or fire suppression, to boost the uptake of atmospheric carbon dioxide. However, a new Yale-led study of...
Data from brain scans can now answer an age-old question asked by parents and teachers everywhere: Are you paying attention?
Using a model of fMRI data collected from 92 individuals performing several types of attention-related tasks, the lab of Yale’s...
The brain has its own housekeeping service, a sophisticated mechanism that cleans up debris that is left over from cellular activity. But scientists have had a hard time figuring out exactly how the brain knows when to initiate this cellular “trash pickup...
It took a global pandemic, but the critical role of messenger RNA in all of life’s functions has taken center stage in the past year with the successful rollout of mRNA vaccines to combat the SARS-Cov-2 virus.
In two new papers published the week of Jan....
The last decade has seen important but insufficient progress in protecting areas that are home to endangered species worldwide, conservation leaders say. As governments prepare to discuss new conservation goals at the 2022 U.N. Biodiversity Conference in...
In the past decade, immunotherapy has helped save the lives of many cancer patients, many with lung cancer, who might have otherwise faced almost certain death sentences. However, only about 20% of patients who received immune therapies, designed to...
From 50,000 years to 6,000 years ago, many of the world’s largest animals, including such iconic grassland grazers as the woolly mammoth, giant bison, and ancient horses, went extinct. The loss of these grazing species triggered a dramatic increase in...
Plants know winter is coming. But exactly how they detect this seasonal change has never been clear.
Yale researchers took a novel approach to understanding a plant’s secrets. They asked one.
And the answer they received — in the form of changes in the...