When scientists probe the human genome for clues about disease, they typically focus on the 2% of our genome that make functional proteins. To explore underexamined elements in the genome, a team of Yale investigators developed a tool, called ERVmap, that...
More than one million people die annually from cerebral malaria, the most lethal form of the disease. A recent study, led by Yale investigators, explores the role of glucose metabolism in the development of the disease, and may hold a key to preventing or...
For human cells to form and move normally during development, a network of protein filaments, known as the actin cytoskeleton, must organize the cell’s shape from within. To help rearrange this network, another protein known as filamin must bind and...
Yale researchers have developed a new imaging technique that captures detailed information about metabolism, which plays a role in many diseases. The novel yet simple technique, which harnesses existing technology, could potentially be used to evaluate...
Yale researchers have tested a new method for directly measuring synaptic loss in individuals with Alzheimer’s disease. The method, which uses PET imaging technology to scan for a specific protein in the brain linked to synapses, has the potential to...
A Yale-led team of researchers have created a vaccine that protects against malaria infection in mouse models, paving the way for the development of a human vaccine that works by targeting the specific protein that parasites use to evade the immune system...
Taking insulin or the most commonly used drug for type 2 diabetes, metformin, failed to either delay or effectively treat the condition in youth, according to a study led by a Yale researcher.
In the study, known as the Restoring Insulin Secretion (RISE...
Obesity, which is on the rise worldwide, has been linked to colon cancer but the mechanism has been a mystery. In a new study, Yale researchers and their co-authors have uncovered how obesity drives tumor growth in mice, revealing potential strategies to...