Why do 80 to 90% of people infected with COVID-19 experience only mild cases while 10 to 20% face more severe or life-threatening symptoms?
Researchers in the lab of Yale’s Richard Flavell decided to pose this question to a mouse, or rather to mice they...
The emergence of COVID-19 variants such as Delta and Omicron have sent scientists scrambling to determine whether existing vaccinations and boosters are still effective against new strains of SARS-Cov-2.
A new response to the rapidly mutating virus might...
Mutations of a gene that regulates formation of blood vessels in the brain of vertebrates can lead to potentially deadly aneurysms in adults, Yale School of Medicine researchers report in the December issue of Nature Medicine.
Saccular brain aneurysms...
In the past decade, immunotherapy has helped save the lives of many cancer patients, many with lung cancer, who might have otherwise faced almost certain death sentences. However, only about 20% of patients who received immune therapies, designed to...
Scientists in recent years have developed ways to measure biological age by tracking chemical changes in DNA that occur naturally as people age but occur at different times in different people. These so-called “epigenetic clocks” have proved to be better...
Yale University researchers have developed a novel vaccine that in guinea pigs offers protection against infection by the bacterium that causes Lyme disease and may also combat other tick-borne diseases, they report Nov. 17 in the journal Science...
A simple RNA molecule jumpstarts the immune system’s “first responders” to viral infection and can even eradicate the SARS-CoV-2 virus in mice with chronic cases of COVID-19, a new Yale School of Medicine study finds.
The molecule, known as SLR14, is a...
The suicide rate among U.S. military veterans is nearly twice as high as that of the general population, and numerous studies have tried to explain why that is. In recent years, for instance, scientists have identified many genes associated with suicidal...
Two of the commonly used coronavirus vaccines provide protection against multiple variants of the virus that causes COVID-19, including the highly infectious Delta variant, a new Yale study has found.
The findings, published Oct. 11 in the journal Nature...
During the worst of the COVID-19 pandemic, overwhelmed doctors and nurses in some places have had to make agonizing decisions about which patients should receive scarce health care resources. Some hospitals have contemplated using a standard measurement...