Müschen named to Arthur H. and Isabel Bunker Professorship at Yale

A professor of medicine and of immunobiology, Dr. Markus Müschen studies oncogenic signaling and clonal evolution in B cell malignancies.
Dr. Markus Müschen
Dr. Markus Müschen

Dr. Markus Müschen, who joined the Yale School of Medicine faculty this fall as the Arthur H. and Isabel Bunker Professor of Medicine and professor of immunobiology, studies oncogenic signaling and clonal evolution in B cell malignancies, including acute lymphoblastic leukemia, the most frequent type of cancer in children and young adults.

At Yale, he will also serve as the inaugural director of the Center of Molecular and Cellular Oncology at Yale Cancer Center and Smilow Cancer Hospital. The new center will serve as a nidus for fostering and mentoring physician-scientists as they advance their laboratory-based research programs to bridge fundamental cancer biology with clinical translation and investigation.

Previously, Müschen was at the City of Hope Comprehensive Cancer Center, where he was the associate director for basic science and the founding chair of the Department of Systems Biology.

Müschen is renowned for new conceptual frameworks for the understanding of B-cell signaling mechanisms and how these mechanisms contribute to malignant transformation and development of drug-resistant leukemia and lymphoma. His laboratory discovered that regulation of energy metabolism functions as a central gatekeeper to prevent the development of leukemia and lymphoma.

Müschen is a Howard Hughes Medical Institute Faculty Scholar, a National Cancer Institute Outstanding Investigator Award (R35) recipient, and formerly a scholar of the Leukemia & Lymphoma Society, a senior investigator of the Wellcome Trust at the University of Cambridge (U.K.), and the Sir Alexander Haddow Professor of the Institute for Cancer Research in London. 

He trained in hematology-oncology at University of Cologne Medical Center in Germany, where he also completed postdoctoral studies in immunology at their Institute for Genetics. He graduated from Heinrich-Heine-Universitat in Düsseldorf, Germany. From 2009 to 2016, Müschen was a tenured professor of laboratory medicine, pathology, and medicine at the University of California-San Francisco (UCSF) and served as program leader of the Hematological Malignancies Program of the UCSF Helen Diller Comprehensive Cancer Center.

Share this with Facebook Share this with X Share this with LinkedIn Share this with Email Print this