Research in the News: From curiosity to cancer drug: Yale researcher conquers ‘valley of death’

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(Illustration by Michael Helfenbein)

The fascination of Yale professor Craig Crews with a natural product compound led a decade later to the approval this summer of a brand-new treatment for multiple myeloma.

The story of how a novel kind of cancer drug, carfilzomib, was born from academic curiosity is the subject of a profile in Aug. 27 issue of the journal Chemical & Engineering News.

“This a great example of how university research can be translated into a medical therapy,” said Crews. “Too often promising ideas get lost in what drug companies call the valley of death.”

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